This short study attempts to address the internal meaning of a famous painting by Salvador Dalí: The Persistence of Memory (1931), using theoretical and methodological tools developed by the “School of Paris” semiotics. Thus, we move from the hierarchical description of the plane of expression (from percepts to formants), to the progressive organization of the form of the content through a semanticization of all the units identified in the previous phases of the analysis. This makes it possible to set up the deep semantics specific to this work and the values it carries during the semiosis process. Thus, the meaning of this statement (visual text) is gradually revealed through a less naive reading of this major work of art history which is at the core of broader cultural concerns both for the artist and all readers: the conceptualization of time through various prisms, both plastic and semantic.